Endocrine Abstracts

The Nottingham Diabetes web site (www.nottinghamdiabetes.nhs.uk) was launched in January 2002 as an information and education resource for people with diabetes and diabetes care teams in Nottingham. It was developed jointly by the two hospital diabetes centres in Nottingham, designed by an independent web designer and funded by the pharmaceutical industry (with no influence over content or acknowledgement on the site).The site contains information about ...

Background: Zoledronate is a nitrogen-containing bisphosphonate (BP) recognised for its antiresorptive potency. The pharmacokinetic/pharmacodynamic of zoledronate remains unclear. Although adverse events from overuse of BP is rare, there have been reports of over-treatment resulting in pathophysiological consequences. The current administration regimen is not tailored to the individual’s therapeutic response to zoledronate. Quantifying post-dose serum con...

Background: The active form of vitamin D, 1,25(OH)2D, plays a key role in regulating calcium and phosphorus metabolism and bone homeostasis. In paediatrics, maintaining optimal 1,25(OH)2D levels is crucial for supporting musculoskeletal growth. The hormone also serves as a diagnostic indicator for multiple disorders such as vitamin-D dependent rickets. Current Literature lacks comprehensive reporting of age-specific reference ranges in pa...